It is possible to create an override for the edit params layout only for the com_content component.

First you will need to create a new folder for the custom layout overrides.
I would choose to create a folder named "overrides" and put it in:

    administrator/templates/isis/html/layouts/overrides

The JLayoutHelper:render method will first search inside this folder when looking for the joomla.edit.params layout. In order to load it, you will need to keep the same structure inside the overrides folder. So the params.php file should be placed like: `/overrides/joomla/edit/params.php`


Then, you will need to create an override for the edit.php template file of the article view, from which you will call the custom layout.


Inside the html folder of the isis temlpate, create a folder for the com_content overrides, name it "com_content", and then a folder for the article view's template files, named "article".
Copy the edit.php file from the component and drop it in the article folder.

Now, inside the edit.php, you can adjust the JLayoutHelper::render method and pass to it a new base path to look for the alternative layout like below:

    <?php echo JLayoutHelper::render('joomla.edit.params', $this, $basePath = JPATH_ADMINISTRATOR .'/templates/isis/html/layouts/overrides'); ?>

This will look for a params.php layout, inside the :
`administrator/templates/isis/html/layouts/overrides/joomla/edit` folder.

You can keep things simpler if you just place the params.php inside the overrides folder and call it like:

    <?php echo JLayoutHelper::render('params', $this, $basePath = JPATH_ADMINISTRATOR .'/templates/isis/html/layouts/overrides'); ?>

Finally, remember to also add index.html files inside any newly created folder.